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5tqu

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==Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor==
==Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor==
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<StructureSection load='5tqu' size='340' side='right' caption='[[5tqu]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='5tqu' size='340' side='right'caption='[[5tqu]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5tqu]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TQU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TQU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5tqu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei_TREU927 Trypanosoma brucei brucei TREU927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TQU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TQU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=I53:2-[2-[[3-(1~{H}-BENZIMIDAZOL-2-YLAMINO)PROPYLAMINO]METHYL]-4,6-BIS(CHLORANYL)INDOL-1-YL]ETHANOL'>I53</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=I53:2-[2-[[3-(1~{H}-BENZIMIDAZOL-2-YLAMINO)PROPYLAMINO]METHYL]-4,6-BIS(CHLORANYL)INDOL-1-YL]ETHANOL'>I53</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tqu OCA], [http://pdbe.org/5tqu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tqu RCSB], [http://www.ebi.ac.uk/pdbsum/5tqu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tqu ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tqu OCA], [https://pdbe.org/5tqu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tqu RCSB], [https://www.ebi.ac.uk/pdbsum/5tqu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tqu ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q38C91_TRYB2 Q38C91_TRYB2]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Methionine--tRNA ligase]]
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[[Category: Large Structures]]
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[[Category: Barros-Alvarez, X]]
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[[Category: Trypanosoma brucei brucei TREU927]]
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[[Category: Hol, W G.J]]
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[[Category: Barros-Alvarez X]]
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[[Category: Inhibitor]]
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[[Category: Hol WGJ]]
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[[Category: Ligase]]
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[[Category: Ligase-ligase inhibitor complex]]
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[[Category: Methionine]]
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[[Category: Synthetase]]
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Current revision

Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor

PDB ID 5tqu

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