This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1uf5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (23:52, 27 December 2023) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1uf5.gif|left|200px]]
 
-
{{Structure
+
==Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-methionine==
-
|PDB= 1uf5 |SIZE=350|CAPTION= <scene name='initialview01'>1uf5</scene>, resolution 1.60&Aring;
+
<StructureSection load='1uf5' size='340' side='right'caption='[[1uf5]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=CDT:4-METHYLSULFANYL-2-UREIDO-BUTYRIC+ACID'>CDT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
+
<table><tr><td colspan='2'>[[1uf5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_sp. Agrobacterium sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UF5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UF5 FirstGlance]. <br>
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/N-carbamoyl-D-amino_acid_hydrolase N-carbamoyl-D-amino acid hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.77 3.5.1.77] </span>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
|GENE=
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CDT:4-METHYLSULFANYL-2-UREIDO-BUTYRIC+ACID'>CDT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-
|DOMAIN=
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uf5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uf5 OCA], [https://pdbe.org/1uf5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uf5 RCSB], [https://www.ebi.ac.uk/pdbsum/1uf5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uf5 ProSAT]</span></td></tr>
-
|RELATEDENTRY=[[1uf4|1UF4]], [[1uf7|1UF7]], [[1uf8|1UF8]]
+
</table>
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uf5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uf5 OCA], [http://www.ebi.ac.uk/pdbsum/1uf5 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1uf5 RCSB]</span>
+
== Function ==
-
}}
+
[https://www.uniprot.org/uniprot/DCAS_AGRSK DCAS_AGRSK] The enzyme catalyzes the hydrolysis of N-carbamoyl-D-amino acids to the corresponding which are useful intermediates in the preparation of beta-lactam antibiotics. Industrial production of beta-lactam antibiotics is now being developed using this enzyme.
-
 
+
== Evolutionary Conservation ==
-
'''Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-methionine'''
+
[[Image:Consurf_key_small.gif|200px|right]]
-
 
+
Check<jmol>
-
 
+
<jmolCheckbox>
-
==About this Structure==
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uf/1uf5_consurf.spt"</scriptWhenChecked>
-
1UF5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Agrobacterium_sp. Agrobacterium sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UF5 OCA].
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Agrobacterium sp.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: N-carbamoyl-D-amino acid hydrolase]]
+
</jmolCheckbox>
-
[[Category: Single protein]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uf5 ConSurf].
-
[[Category: Aoki, M.]]
+
<div style="clear:both"></div>
-
[[Category: Hashimoto, H.]]
+
__TOC__
-
[[Category: Ikenaka, Y.]]
+
</StructureSection>
-
[[Category: Morikawa, H.]]
+
[[Category: Agrobacterium sp]]
-
[[Category: Nakai, T.]]
+
[[Category: Large Structures]]
-
[[Category: Sato, M.]]
+
[[Category: Aoki M]]
-
[[Category: Shimizu, T.]]
+
[[Category: Hashimoto H]]
-
[[Category: Takahashi, S.]]
+
[[Category: Ikenaka Y]]
-
[[Category: hydrolase]]
+
[[Category: Morikawa H]]
-
 
+
[[Category: Nakai T]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:09:29 2008''
+
[[Category: Sato M]]
 +
[[Category: Shimizu T]]
 +
[[Category: Takahashi S]]

Current revision

Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase complexed with N-carbamyl-D-methionine

PDB ID 1uf5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1uf5"
Personal tools