1ujm

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[[Image:1ujm.gif|left|200px]]
 
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{{Structure
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==Crystal structure of aldehyde reductase 2 from Sporobolomyces salmonicolor AKU4429==
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|PDB= 1ujm |SIZE=350|CAPTION= <scene name='initialview01'>1ujm</scene>, resolution 2.00&Aring;
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<StructureSection load='1ujm' size='340' side='right'caption='[[1ujm]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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<table><tr><td colspan='2'>[[1ujm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sporidiobolus_salmonicolor Sporidiobolus salmonicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UJM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UJM FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Alcohol_dehydrogenase_(NADP(+)) Alcohol dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.2 1.1.1.2] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ujm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ujm OCA], [https://pdbe.org/1ujm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ujm RCSB], [https://www.ebi.ac.uk/pdbsum/1ujm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ujm ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ujm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ujm OCA], [http://www.ebi.ac.uk/pdbsum/1ujm PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ujm RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/ALD2_SPOSA ALD2_SPOSA] Catalyzes the asymmetric reduction of o-substituted aliphatic and aromatic aldehydes and ketones to an S-enantiomer. Reduces ethyl 4-chloro-3-oxobutanoate to ethyl (S)-4-chloro-3-hydroxybutanoate.<ref>PMID:10583966</ref> [REFERENCE:2]
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== Evolutionary Conservation ==
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'''Crystal structure of aldehyde reductase 2 from Sporobolomyces salmonicolor AKU4429'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uj/1ujm_consurf.spt"</scriptWhenChecked>
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1UJM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sporidiobolus_salmonicolor Sporidiobolus salmonicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UJM OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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[[Category: Alcohol dehydrogenase (NADP(+))]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Single protein]]
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ujm ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Sporidiobolus salmonicolor]]
[[Category: Sporidiobolus salmonicolor]]
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[[Category: Iguchi, A.]]
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[[Category: Iguchi A]]
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[[Category: Kamitori, S.]]
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[[Category: Kamitori S]]
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[[Category: Kita, K.]]
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[[Category: Kita K]]
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[[Category: Ohtaki, A.]]
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[[Category: Ohtaki A]]
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[[Category: nadph-dependent enzyme]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:11:10 2008''
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Current revision

Crystal structure of aldehyde reductase 2 from Sporobolomyces salmonicolor AKU4429

PDB ID 1ujm

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