This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5gxq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:45, 2 August 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==The crystal structure of the nucleosome containing H3.6==
==The crystal structure of the nucleosome containing H3.6==
-
<StructureSection load='5gxq' size='340' side='right' caption='[[5gxq]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
+
<StructureSection load='5gxq' size='340' side='right'caption='[[5gxq]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5gxq]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GXQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GXQ FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5gxq]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GXQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GXQ FirstGlance]. <br>
-
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gxq OCA], [http://pdbe.org/5gxq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gxq RCSB], [http://www.ebi.ac.uk/pdbsum/5gxq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gxq ProSAT]</span></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gxq OCA], [https://pdbe.org/5gxq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gxq RCSB], [https://www.ebi.ac.uk/pdbsum/5gxq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gxq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/H2B1J_HUMAN H2B1J_HUMAN]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref> Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.<ref>PMID:11859126</ref> <ref>PMID:12860195</ref> <ref>PMID:15019208</ref>
+
[https://www.uniprot.org/uniprot/A0A1X8XL64_HUMAN A0A1X8XL64_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 17: Line 18:
</div>
</div>
<div class="pdbe-citations 5gxq" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5gxq" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Histone 3D structures|Histone 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Horikoshi, N]]
+
[[Category: Homo sapiens]]
-
[[Category: Kurumizaka, H]]
+
[[Category: Large Structures]]
-
[[Category: Taguchi, H]]
+
[[Category: Horikoshi N]]
-
[[Category: Xie, Y]]
+
[[Category: Kurumizaka H]]
-
[[Category: Chromatin]]
+
[[Category: Taguchi H]]
-
[[Category: Histone variant]]
+
[[Category: Xie Y]]
-
[[Category: Nucleosome]]
+
-
[[Category: Structural protein-dna complex]]
+

Current revision

The crystal structure of the nucleosome containing H3.6

PDB ID 5gxq

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5gxq"
Personal tools