5nxd

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m (Protected "5nxd" [edit=sysop:move=sysop])
Current revision (12:14, 22 November 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5nxd is ON HOLD
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==LIM Domain Kinase 2 (LIMK2) In Complex With TH-300==
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<StructureSection load='5nxd' size='340' side='right'caption='[[5nxd]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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Authors: Mathea, S., Salah, E., Hanke, T., Newman, J.A., Oerum, S., Wang, D., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.N., Knapp, S.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5nxd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NXD FirstGlance]. <br>
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Description: LIM Domain Kinase 2 (LIMK2)In Complex With TH-300
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9D8:4-[(3-CHLOROPHENYL)SULFAMOYL]-~{N}-(PHENYLMETHYL)-~{N}-PROPYL-BENZAMIDE'>9D8</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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[[Category: Oerum, S]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nxd OCA], [https://pdbe.org/5nxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nxd RCSB], [https://www.ebi.ac.uk/pdbsum/5nxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nxd ProSAT]</span></td></tr>
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[[Category: Mathea, S]]
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</table>
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[[Category: Arrowsmith, C.H]]
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== Function ==
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[[Category: Burgess-Brown, N]]
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[https://www.uniprot.org/uniprot/LIMK2_HUMAN LIMK2_HUMAN] Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro.<ref>PMID:10436159</ref> <ref>PMID:11018042</ref>
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[[Category: Wang, D]]
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== References ==
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[[Category: Von Delft, F]]
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<references/>
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[[Category: Bullock, A.N]]
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__TOC__
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[[Category: Knapp, S]]
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</StructureSection>
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[[Category: Hanke, T]]
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[[Category: Homo sapiens]]
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[[Category: Edwards, A.M]]
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[[Category: Large Structures]]
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[[Category: Newman, J.A]]
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[[Category: Arrowsmith CH]]
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[[Category: Salah, E]]
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[[Category: Bountra C]]
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[[Category: Bountra, C]]
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[[Category: Bullock AN]]
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[[Category: Burgess-Brown N]]
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[[Category: Edwards AM]]
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[[Category: Hanke T]]
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[[Category: Knapp S]]
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[[Category: Mathea S]]
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[[Category: Newman JA]]
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[[Category: Oerum S]]
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[[Category: Salah E]]
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[[Category: Wang D]]
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[[Category: Von Delft F]]

Current revision

LIM Domain Kinase 2 (LIMK2) In Complex With TH-300

PDB ID 5nxd

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