1vdl

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[[Image:1vdl.gif|left|200px]]
 
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{{Structure
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==Solution Structure of RSGI RUH-013, a UBA domain in Mouse cDNA==
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|PDB= 1vdl |SIZE=350|CAPTION= <scene name='initialview01'>1vdl</scene>
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<StructureSection load='1vdl' size='340' side='right'caption='[[1vdl]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1vdl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VDL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VDL FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquitin_thiolesterase Ubiquitin thiolesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.2.15 3.1.2.15] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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|GENE= RIKEN cDNA 2610101O11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vdl OCA], [https://pdbe.org/1vdl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vdl RCSB], [https://www.ebi.ac.uk/pdbsum/1vdl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vdl ProSAT], [https://www.topsan.org/Proteins/RSGI/1vdl TOPSAN]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vdl OCA], [http://www.ebi.ac.uk/pdbsum/1vdl PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1vdl RCSB]</span>
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[https://www.uniprot.org/uniprot/UBP25_MOUSE UBP25_MOUSE] Deubiquitinating enzyme that hydrolyzes ubiquitin moieties conjugated to substrates and thus, functions to process newly synthesized Ubiquitin, to recycle ubiquitin molecules or to edit polyubiquitin chains and prevents proteasomal degradation of substrates. Hydrolyzes both 'Lys-48'- and 'Lys-63'-linked tetraubiquitin chains (By similarity).<ref>PMID:16501887</ref> The muscle-specific isoform (USP25m) may have a role in the regulation of muscular differentiation and function.<ref>PMID:16501887</ref>
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vd/1vdl_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vdl ConSurf].
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<div style="clear:both"></div>
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'''Solution Structure of RSGI RUH-013, a UBA domain in Mouse cDNA'''
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==See Also==
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*[[Thioesterase 3D structures|Thioesterase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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1VDL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VDL OCA].
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Doi-Katayama Y]]
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[[Category: Ubiquitin thiolesterase]]
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[[Category: Hirota H]]
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[[Category: Doi-Katayama, Y.]]
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[[Category: Kigawa T]]
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[[Category: Hirota, H.]]
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[[Category: Koshiba S]]
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[[Category: Kigawa, T.]]
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[[Category: Saito K]]
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[[Category: Koshiba, S.]]
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[[Category: Yokoyama S]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Saito, K.]]
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[[Category: Yokoyama, S.]]
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[[Category: mouse cdna]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: structural genomic]]
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[[Category: uba domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:22:55 2008''
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Current revision

Solution Structure of RSGI RUH-013, a UBA domain in Mouse cDNA

PDB ID 1vdl

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