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5x1i

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==Vanillate/3-O-methylgallate O-demethylase, LigM, substrate free form==
==Vanillate/3-O-methylgallate O-demethylase, LigM, substrate free form==
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<StructureSection load='5x1i' size='340' side='right' caption='[[5x1i]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='5x1i' size='340' side='right'caption='[[5x1i]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5x1i]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X1I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5X1I FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5x1i]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Sphingobium_sp._SYK-6 Sphingobium sp. SYK-6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X1I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5X1I FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5x1j|5x1j]], [[5x1k|5x1k]], [[5x1l|5x1l]], [[5x1m|5x1m]], [[5x1n|5x1n]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5x1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x1i OCA], [http://pdbe.org/5x1i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5x1i RCSB], [http://www.ebi.ac.uk/pdbsum/5x1i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5x1i ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5x1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x1i OCA], [https://pdbe.org/5x1i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5x1i RCSB], [https://www.ebi.ac.uk/pdbsum/5x1i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5x1i ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LIGM_SPHSK LIGM_SPHSK] Involved in the catabolism of vanillate and syringate. Catalyzes the transfer of a methyl moiety from vanillate or 3-O-methylgallate (3MGA) to tetrahydrofolate, forming protocatechuate (PCA) or gallate, respectively, and methyl-tetrahydrofolate. Has similar activities with both substrates (PubMed:15743951). Cannot use syringate (PubMed:15743951). Uses an ordered, sequential kinetic mechanism (PubMed:28373573).<ref>PMID:15743951</ref> <ref>PMID:28373573</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Harada, A]]
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[[Category: Large Structures]]
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[[Category: Senda, T]]
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[[Category: Sphingobium sp. SYK-6]]
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[[Category: Lignin]]
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[[Category: Harada A]]
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[[Category: Oxidoreductase]]
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[[Category: Senda T]]
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[[Category: Sphingobium sp. syk-6]]
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Current revision

Vanillate/3-O-methylgallate O-demethylase, LigM, substrate free form

PDB ID 5x1i

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