5lbx

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==Structure of the T175V Etr1p mutant in the trigonal form P312 in complex with NADP and crotonyl-CoA==
==Structure of the T175V Etr1p mutant in the trigonal form P312 in complex with NADP and crotonyl-CoA==
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<StructureSection load='5lbx' size='340' side='right' caption='[[5lbx]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='5lbx' size='340' side='right'caption='[[5lbx]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5lbx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LBX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LBX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5lbx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_tropicalis Candida tropicalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LBX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LBX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COO:CROTONYL+COENZYME+A'>COO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lbx OCA], [http://pdbe.org/5lbx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lbx RCSB], [http://www.ebi.ac.uk/pdbsum/5lbx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lbx ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COO:CROTONYL+COENZYME+A'>COO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lbx OCA], [https://pdbe.org/5lbx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lbx RCSB], [https://www.ebi.ac.uk/pdbsum/5lbx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lbx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ETR1_CANTR ETR1_CANTR]] Required for respiration and the maintenance of the mitochondrial compartment. May have a role in the mitochondrial synthesis of fatty acids.<ref>PMID:11509667</ref>
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[https://www.uniprot.org/uniprot/ETR1_CANTR ETR1_CANTR] Required for respiration and the maintenance of the mitochondrial compartment. May have a role in the mitochondrial synthesis of fatty acids.<ref>PMID:11509667</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5lbx" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5lbx" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Erb, T J]]
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[[Category: Candida tropicalis]]
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[[Category: Rosenthal, R G]]
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[[Category: Large Structures]]
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[[Category: Shima, S]]
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[[Category: Erb TJ]]
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[[Category: Voegeli, B]]
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[[Category: Rosenthal RG]]
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[[Category: Wagner, T]]
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[[Category: Shima S]]
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[[Category: Crotonyl-coa]]
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[[Category: Voegeli B]]
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[[Category: Enzyme]]
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[[Category: Wagner T]]
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[[Category: Mitochondria]]
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[[Category: Mutant]]
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[[Category: Nadp]]
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[[Category: Negative catalysis]]
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[[Category: Oxidoreductase]]
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[[Category: Reductase]]
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Current revision

Structure of the T175V Etr1p mutant in the trigonal form P312 in complex with NADP and crotonyl-CoA

PDB ID 5lbx

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