This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5lca

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:56, 11 October 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==VIM-2 metallo-beta-lactamase in complex with 3-oxo-2-(3-(trifluoromethyl)phenyl)isoindoline-4-carboxylic acid (compound 17)==
==VIM-2 metallo-beta-lactamase in complex with 3-oxo-2-(3-(trifluoromethyl)phenyl)isoindoline-4-carboxylic acid (compound 17)==
-
<StructureSection load='5lca' size='340' side='right' caption='[[5lca]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
+
<StructureSection load='5lca' size='340' side='right'caption='[[5lca]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5lca]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LCA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LCA FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5lca]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LCA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LCA FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B06:3-OXIDANYLIDENE-2-[3-(TRIFLUOROMETHYL)PHENYL]-1~{H}-ISOINDOLE-4-CARBOXYLIC+ACID'>B06</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.93&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lca OCA], [http://pdbe.org/5lca PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lca RCSB], [http://www.ebi.ac.uk/pdbsum/5lca PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lca ProSAT]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B06:3-OXIDANYLIDENE-2-[3-(TRIFLUOROMETHYL)PHENYL]-1~{H}-ISOINDOLE-4-CARBOXYLIC+ACID'>B06</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lca OCA], [https://pdbe.org/5lca PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lca RCSB], [https://www.ebi.ac.uk/pdbsum/5lca PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lca ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q9K2N0_PSEAI Q9K2N0_PSEAI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 18: Line 21:
==See Also==
==See Also==
-
*[[Beta-lactamase|Beta-lactamase]]
+
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Brem, J]]
+
[[Category: Large Structures]]
-
[[Category: Li, G B]]
+
[[Category: Pseudomonas aeruginosa]]
-
[[Category: McDonough, M A]]
+
[[Category: Brem J]]
-
[[Category: Schofield, C J]]
+
[[Category: Li G-B]]
-
[[Category: Antibiotic resistance]]
+
[[Category: McDonough MA]]
-
[[Category: Complex]]
+
[[Category: Schofield CJ]]
-
[[Category: Hydrolase]]
+
-
[[Category: Inhibitor]]
+
-
[[Category: Metallo-beta-lactamase]]
+

Current revision

VIM-2 metallo-beta-lactamase in complex with 3-oxo-2-(3-(trifluoromethyl)phenyl)isoindoline-4-carboxylic acid (compound 17)

PDB ID 5lca

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools