5le1

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==VIM-2 metallo-beta-lactamase in complex with 2-(2-chloro-6-fluorobenzyl)-3-oxoisoindoline-4-carboxylic acid (compound 16)==
==VIM-2 metallo-beta-lactamase in complex with 2-(2-chloro-6-fluorobenzyl)-3-oxoisoindoline-4-carboxylic acid (compound 16)==
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<StructureSection load='5le1' size='340' side='right' caption='[[5le1]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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<StructureSection load='5le1' size='340' side='right'caption='[[5le1]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5le1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LE1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LE1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5le1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LE1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6UW:2-[(2-CHLORANYL-6-FLUORANYL-PHENYL)METHYL]-3-OXIDANYLIDENE-1~{H}-ISOINDOLE-4-CARBOXYLIC+ACID'>6UW</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5le1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5le1 OCA], [http://pdbe.org/5le1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5le1 RCSB], [http://www.ebi.ac.uk/pdbsum/5le1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5le1 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6UW:2-[(2-CHLORANYL-6-FLUORANYL-PHENYL)METHYL]-3-OXIDANYLIDENE-1~{H}-ISOINDOLE-4-CARBOXYLIC+ACID'>6UW</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5le1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5le1 OCA], [https://pdbe.org/5le1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5le1 RCSB], [https://www.ebi.ac.uk/pdbsum/5le1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5le1 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9K2N0_PSEAI Q9K2N0_PSEAI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Beta-lactamase|Beta-lactamase]]
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Brem, J]]
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[[Category: Large Structures]]
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[[Category: Li, G B]]
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[[Category: Pseudomonas aeruginosa]]
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[[Category: McDonough, M A]]
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[[Category: Brem J]]
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[[Category: Schofield, C J]]
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[[Category: Li G-B]]
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[[Category: Antibiotic resistance]]
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[[Category: McDonough MA]]
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[[Category: Complex]]
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[[Category: Schofield CJ]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor]]
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[[Category: Metallo-beta-lactamase]]
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Current revision

VIM-2 metallo-beta-lactamase in complex with 2-(2-chloro-6-fluorobenzyl)-3-oxoisoindoline-4-carboxylic acid (compound 16)

PDB ID 5le1

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