5nzx

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m (Protected "5nzx" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 5nzx is ON HOLD
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==Crystal structure of DNA cross-link repair protein 1A in complex with Ceftriaxone (alternative site)==
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<StructureSection load='5nzx' size='340' side='right'caption='[[5nzx]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
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Authors: Newman, J.A., Aitkenhead, H, Kupinska, K, Burgess-Brown, N.A., Talon, R, Krojer, T, von Delft, F, Arrowsmith, C.H., Edwards, A, Bountra, C, Gileadi, O
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5nzx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NZX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NZX FirstGlance]. <br>
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Description: Crystal structure of DNA cross-link repair protein 1A in complex with Ceftriaxone (alternative site)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.47&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9F2:Ceftriaxone'>9F2</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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[[Category: Aitkenhead, H, Kupinska, K, Burgess-Brown, N.A]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nzx OCA], [https://pdbe.org/5nzx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nzx RCSB], [https://www.ebi.ac.uk/pdbsum/5nzx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nzx ProSAT]</span></td></tr>
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[[Category: Talon, R, Krojer, T, Von Delft, F, Arrowsmith, C.H]]
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</table>
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[[Category: Newman, J.A]]
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== Function ==
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[[Category: Edwards, A, Bountra, C, Gileadi, O]]
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[https://www.uniprot.org/uniprot/DCR1A_HUMAN DCR1A_HUMAN] May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons.<ref>PMID:15542852</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Aitkenhead H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra C]]
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[[Category: Burgess-Brown NA]]
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[[Category: Edwards A]]
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[[Category: Gileadi O]]
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[[Category: Krojer T]]
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[[Category: Kupinska K]]
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[[Category: Newman JA]]
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[[Category: Talon R]]
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[[Category: Von Delft F]]

Current revision

Crystal structure of DNA cross-link repair protein 1A in complex with Ceftriaxone (alternative site)

PDB ID 5nzx

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