5xmk
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the ATP-bound Vps4 mutant-E233Q complex with Vta1 (masked)== | |
| + | <SX load='5xmk' size='340' side='right' viewer='molstar' caption='[[5xmk]], [[Resolution|resolution]] 4.18Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5xmk]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XMK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XMK FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.18Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xmk OCA], [https://pdbe.org/5xmk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xmk RCSB], [https://www.ebi.ac.uk/pdbsum/5xmk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xmk ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VPS4_YEAST VPS4_YEAST] Involved in the transport of biosynthetic membrane proteins from the prevacuolar/endosomal compartment to the vacuole. Required for multivesicular body (MVB) protein sorting. Catalyzes the ATP-dependent dissociation of class E VPS proteins from endosomal membranes, such as the disassembly of the ESCRT-III complex.<ref>PMID:11329380</ref> <ref>PMID:9155008</ref> <ref>PMID:9606181</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Vacuolar protein sorting-associated protein 3D structures|Vacuolar protein sorting-associated protein 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| + | </SX> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Fan F]] | ||
| + | [[Category: Li L]] | ||
| + | [[Category: Li X]] | ||
| + | [[Category: Sui S]] | ||
| + | [[Category: Sun S]] | ||
| + | [[Category: Wang H]] | ||
| + | [[Category: Wang X]] | ||
| + | [[Category: Yang F]] | ||
Current revision
Cryo-EM structure of the ATP-bound Vps4 mutant-E233Q complex with Vta1 (masked)
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Categories: Large Structures | Saccharomyces cerevisiae S288C | Fan F | Li L | Li X | Sui S | Sun S | Wang H | Wang X | Yang F
