5nxd
From Proteopedia
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==LIM Domain Kinase 2 (LIMK2) In Complex With TH-300== | ==LIM Domain Kinase 2 (LIMK2) In Complex With TH-300== | ||
| - | <StructureSection load='5nxd' size='340' side='right' caption='[[5nxd]], [[Resolution|resolution]] 1.90Å' scene=''> | + | <StructureSection load='5nxd' size='340' side='right'caption='[[5nxd]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5nxd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NXD OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5nxd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NXD FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9D8:4-[(3-CHLOROPHENYL)SULFAMOYL]-~{N}-(PHENYLMETHYL)-~{N}-PROPYL-BENZAMIDE'>9D8</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9D8:4-[(3-CHLOROPHENYL)SULFAMOYL]-~{N}-(PHENYLMETHYL)-~{N}-PROPYL-BENZAMIDE'>9D8</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nxd OCA], [https://pdbe.org/5nxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nxd RCSB], [https://www.ebi.ac.uk/pdbsum/5nxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nxd ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/LIMK2_HUMAN LIMK2_HUMAN] Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro.<ref>PMID:10436159</ref> <ref>PMID:11018042</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
| - | [[Category: Bountra | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bullock | + | [[Category: Bountra C]] |
| - | [[Category: Burgess-Brown | + | [[Category: Bullock AN]] |
| - | + | [[Category: Burgess-Brown N]] | |
| - | [[Category: Edwards | + | [[Category: Edwards AM]] |
| - | [[Category: Hanke | + | [[Category: Hanke T]] |
| - | [[Category: Knapp | + | [[Category: Knapp S]] |
| - | [[Category: Mathea | + | [[Category: Mathea S]] |
| - | [[Category: Newman | + | [[Category: Newman JA]] |
| - | [[Category: Oerum | + | [[Category: Oerum S]] |
| - | [[Category: Salah | + | [[Category: Salah E]] |
| - | [[Category: Wang | + | [[Category: Wang D]] |
| - | [[Category: | + | [[Category: Von Delft F]] |
| - | + | ||
Current revision
LIM Domain Kinase 2 (LIMK2) In Complex With TH-300
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Bullock AN | Burgess-Brown N | Edwards AM | Hanke T | Knapp S | Mathea S | Newman JA | Oerum S | Salah E | Wang D | Von Delft F
