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4mng

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==Structure of the DP10.7 TCR with CD1d-sulfatide==
==Structure of the DP10.7 TCR with CD1d-sulfatide==
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<StructureSection load='4mng' size='340' side='right' caption='[[4mng]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
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<StructureSection load='4mng' size='340' side='right'caption='[[4mng]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4mng]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MNG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MNG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4mng]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MNG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MNG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIS:(15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE'>CIS</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.0058&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mng OCA], [http://pdbe.org/4mng PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mng RCSB], [http://www.ebi.ac.uk/pdbsum/4mng PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mng ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIS:(15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE'>CIS</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mng OCA], [https://pdbe.org/4mng PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mng RCSB], [https://www.ebi.ac.uk/pdbsum/4mng PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mng ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. [[http://www.uniprot.org/uniprot/CD1D_HUMAN CD1D_HUMAN]] Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.<ref>PMID:17475845</ref>
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[https://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Beta-2 microglobulin|Beta-2 microglobulin]]
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*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
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*[[CD1|CD1]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Adams, E J]]
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[[Category: Homo sapiens]]
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[[Category: Luoma, A M]]
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[[Category: Large Structures]]
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[[Category: Cd1]]
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[[Category: Mus musculus]]
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[[Category: Cell-surface receptor]]
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[[Category: Adams EJ]]
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[[Category: Gamma delta t cell]]
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[[Category: Luoma AM]]
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[[Category: Glycoprotein]]
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[[Category: Histocompatibility antigen]]
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[[Category: Human]]
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[[Category: Immune system]]
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[[Category: Immunglobulin]]
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[[Category: Immunological]]
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[[Category: Intestinal epithelial lymphocyte]]
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[[Category: Lipid binding]]
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[[Category: Lymphocyte]]
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[[Category: Myelin]]
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[[Category: Self-ligand]]
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[[Category: Self-recognition]]
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[[Category: T cell recognition]]
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Current revision

Structure of the DP10.7 TCR with CD1d-sulfatide

PDB ID 4mng

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