5g21
From Proteopedia
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==Leishmania major N-myristoyltransferase in complex with a quinoline inhibitor (compound 26).== | ==Leishmania major N-myristoyltransferase in complex with a quinoline inhibitor (compound 26).== | ||
| - | <StructureSection load='5g21' size='340' side='right' caption='[[5g21]], [[Resolution|resolution]] 1.50Å' scene=''> | + | <StructureSection load='5g21' size='340' side='right'caption='[[5g21]], [[Resolution|resolution]] 1.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5g21]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G21 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5g21]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G21 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5G21 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene>, <scene name='pdbligand=YN4:ETHYL+4-[(2-CYANOETHYL)SULFANYL]-6-{[6-(PIPERAZIN-1-YL)'>YN4</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene>, <scene name='pdbligand=YN4:ETHYL+4-[(2-CYANOETHYL)SULFANYL]-6-{[6-(PIPERAZIN-1-YL)'>YN4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5g21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g21 OCA], [https://pdbe.org/5g21 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5g21 RCSB], [https://www.ebi.ac.uk/pdbsum/5g21 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5g21 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/Q4Q5S8_LEIMA Q4Q5S8_LEIMA] Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins (By similarity). |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Bell | + | [[Category: Leishmania major]] |
| - | [[Category: Brannigan | + | [[Category: Bell AS]] |
| - | [[Category: Goncalves | + | [[Category: Brannigan JA]] |
| - | [[Category: Laporte | + | [[Category: Goncalves V]] |
| - | [[Category: Leatherbarrow | + | [[Category: Laporte A]] |
| - | [[Category: Roberts | + | [[Category: Leatherbarrow RJ]] |
| - | [[Category: Tate | + | [[Category: Roberts SM]] |
| - | [[Category: Wilkinson | + | [[Category: Tate EW]] |
| - | + | [[Category: Wilkinson AJ]] | |
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Current revision
Leishmania major N-myristoyltransferase in complex with a quinoline inhibitor (compound 26).
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