3io4
From Proteopedia
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==Huntingtin amino-terminal region with 17 Gln residues - Crystal C90== | ==Huntingtin amino-terminal region with 17 Gln residues - Crystal C90== | ||
- | <StructureSection load='3io4' size='340' side='right' caption='[[3io4]], [[Resolution|resolution]] 3.63Å' scene=''> | + | <StructureSection load='3io4' size='340' side='right'caption='[[3io4]], [[Resolution|resolution]] 3.63Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3io4]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IO4 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[3io4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O157:H7 Escherichia coli O157:H7] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IO4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IO4 FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.63Å</td></tr> |
- | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3io4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3io4 OCA], [https://pdbe.org/3io4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3io4 RCSB], [https://www.ebi.ac.uk/pdbsum/3io4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3io4 ProSAT]</span></td></tr> |
</table> | </table> | ||
+ | == Disease == | ||
+ | [https://www.uniprot.org/uniprot/HD_HUMAN HD_HUMAN] Juvenile Huntington disease;Huntington disease. The disease is caused by mutations affecting the gene represented in this entry. | ||
== Function == | == Function == | ||
- | [[ | + | [https://www.uniprot.org/uniprot/HD_HUMAN HD_HUMAN] May play a role in microtubule-mediated transport or vesicle function.[https://www.uniprot.org/uniprot/MALE_ECO57 MALE_ECO57] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
- | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/io/3io4_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/io/3io4_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Escherichia coli O157:H7]] |
- | + | [[Category: Homo sapiens]] | |
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Bezprozvanny I]] |
- | [[Category: | + | [[Category: Chelliah Y]] |
- | [[Category: | + | [[Category: Kim MW]] |
- | [[Category: | + | [[Category: Kim SW]] |
- | [[Category: | + | [[Category: Otwinowski Z]] |
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Current revision
Huntingtin amino-terminal region with 17 Gln residues - Crystal C90
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