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5obe

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(New page: ==X-ray structure of the adduct formed upon reaction of ribonuclease A with the compound fac-[RuII(CO)3Cl2(N3-MBI), MBI=methyl-benzimidazole== <StructureSection load='5obe' size='340' sid...)
Current revision (09:39, 6 December 2023) (edit) (undo)
 
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==X-ray structure of the adduct formed upon reaction of ribonuclease A with the compound fac-[RuII(CO)3Cl2(N3-MBI), MBI=methyl-benzimidazole==
==X-ray structure of the adduct formed upon reaction of ribonuclease A with the compound fac-[RuII(CO)3Cl2(N3-MBI), MBI=methyl-benzimidazole==
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<StructureSection load='5obe' size='340' side='right' caption='[[5obe]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
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<StructureSection load='5obe' size='340' side='right'caption='[[5obe]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5obe]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OBE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OBE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5obe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OBE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9Q8:tris(oxidaniumylidynemethyl)-tris(oxidanyl)ruthenium'>9Q8</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=RU2:pentakis(oxidaniumyl)-(oxidaniumylidynemethyl)ruthenium'>RU2</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9Q8:tris(oxidaniumylidynemethyl)-tris(oxidanyl)ruthenium'>9Q8</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=RU2:pentakis(oxidaniumyl)-(oxidaniumylidynemethyl)ruthenium'>RU2</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5obe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5obe OCA], [http://pdbe.org/5obe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5obe RCSB], [http://www.ebi.ac.uk/pdbsum/5obe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5obe ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5obe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5obe OCA], [https://pdbe.org/5obe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5obe RCSB], [https://www.ebi.ac.uk/pdbsum/5obe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5obe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN]] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
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[https://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5obe" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5obe" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Pancreatic ribonuclease]]
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[[Category: Large Structures]]
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[[Category: Ferraro, G]]
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[[Category: Ferraro G]]
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[[Category: Merlino, A]]
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[[Category: Merlino A]]
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[[Category: Pontillo, N]]
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[[Category: Pontillo N]]
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[[Category: Co releasing molecule]]
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[[Category: Hydrolase]]
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[[Category: Protein-metallodrug interaction]]
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Current revision

X-ray structure of the adduct formed upon reaction of ribonuclease A with the compound fac-[RuII(CO)3Cl2(N3-MBI), MBI=methyl-benzimidazole

PDB ID 5obe

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