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5mog

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==Oryza sativa phytoene desaturase inhibited by norflurazon==
==Oryza sativa phytoene desaturase inhibited by norflurazon==
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<StructureSection load='5mog' size='340' side='right' caption='[[5mog]], [[Resolution|resolution]] 2.77&Aring;' scene=''>
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<StructureSection load='5mog' size='340' side='right'caption='[[5mog]], [[Resolution|resolution]] 2.77&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5mog]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MOG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MOG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5mog]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa_Indica_Group Oryza sativa Indica Group]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MOG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MOG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=NRF:Norflurazon'>NRF</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.77&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mog FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mog OCA], [http://pdbe.org/5mog PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mog RCSB], [http://www.ebi.ac.uk/pdbsum/5mog PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mog ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=NRF:Norflurazon'>NRF</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mog FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mog OCA], [https://pdbe.org/5mog PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mog RCSB], [https://www.ebi.ac.uk/pdbsum/5mog PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mog ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CRTI_ORYSI CRTI_ORYSI]] This enzyme converts phytoene into zeta-carotene via the intermediary of phytofluene by the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene.
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[https://www.uniprot.org/uniprot/PDS_ORYSI PDS_ORYSI] Converts phytoene into zeta-carotene via the intermediary of phytofluene by the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene with a concomitant isomerization of two neighboring double bonds at the C9 and C9' positions from trans to cis. Active with decylplastoquinone (DPQ) as substrate (PubMed:26147209, PubMed:29176862). Also active with other benzoquinones, which are strongly preferred over naphthoquinones as substrates (PubMed:26147209).<ref>PMID:26147209</ref> <ref>PMID:29176862</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beyer, P]]
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[[Category: Large Structures]]
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[[Category: Brausemann, A]]
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[[Category: Oryza sativa Indica Group]]
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[[Category: Einsle, O]]
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[[Category: Beyer P]]
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[[Category: Gemmecker, S]]
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[[Category: Brausemann A]]
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[[Category: Koschmieder, J]]
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[[Category: Einsle O]]
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[[Category: Carotenoid biosynthesis]]
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[[Category: Gemmecker S]]
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[[Category: Inhibitor]]
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[[Category: Koschmieder J]]
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[[Category: Isomerase]]
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[[Category: Oxidoreductase]]
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Current revision

Oryza sativa phytoene desaturase inhibited by norflurazon

PDB ID 5mog

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