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5wr3

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==Thermolysin, SFX liganded form with water-based carrier==
==Thermolysin, SFX liganded form with water-based carrier==
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<StructureSection load='5wr3' size='340' side='right' caption='[[5wr3]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='5wr3' size='340' side='right'caption='[[5wr3]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5wr3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WR3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WR3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5wr3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WR3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WR3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NX6:N-[(BENZYLOXY)CARBONYL]-L-ASPARTIC+ACID'>NX6</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5wr6|5wr6]], [[5wr5|5wr5]], [[5wr4|5wr4]], [[5wr2|5wr2]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NX6:N-[(BENZYLOXY)CARBONYL]-L-ASPARTIC+ACID'>NX6</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wr3 OCA], [https://pdbe.org/5wr3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wr3 RCSB], [https://www.ebi.ac.uk/pdbsum/5wr3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wr3 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wr3 OCA], [http://pdbe.org/5wr3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wr3 RCSB], [http://www.ebi.ac.uk/pdbsum/5wr3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wr3 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/THER_GEOSE THER_GEOSE]] Extracellular zinc metalloprotease.<ref>PMID:3149972</ref>
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[https://www.uniprot.org/uniprot/THER_GEOSE THER_GEOSE] Extracellular zinc metalloprotease.<ref>PMID:3149972</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5wr3" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5wr3" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Thermolysin 3D structures|Thermolysin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Thermolysin]]
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[[Category: Geobacillus stearothermophilus]]
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[[Category: Kunishima, N]]
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[[Category: Large Structures]]
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[[Category: Matsuura, Y]]
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[[Category: Kunishima N]]
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[[Category: Naitow, H]]
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[[Category: Matsuura Y]]
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[[Category: Hydrolase]]
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[[Category: Naitow H]]
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[[Category: Microcrystal]]
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[[Category: Serial femtosecond crystallography]]
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[[Category: Structure-based drug design]]
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[[Category: X-ray free-electron laser]]
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Current revision

Thermolysin, SFX liganded form with water-based carrier

PDB ID 5wr3

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