1wfv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:37, 9 May 2024) (edit) (undo)
 
(14 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1wfv.gif|left|200px]]
 
-
{{Structure
+
==Solution structure of the fifth PDZ domain of human membrane associated guanylate kinase inverted-2 (KIAA0705 protein)==
-
|PDB= 1wfv |SIZE=350|CAPTION= <scene name='initialview01'>1wfv</scene>
+
<StructureSection load='1wfv' size='340' side='right'caption='[[1wfv]]' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND=
+
<table><tr><td colspan='2'>[[1wfv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WFV FirstGlance]. <br>
-
|ACTIVITY=
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
|GENE= KAZUSA cDNA hg03359 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wfv OCA], [https://pdbe.org/1wfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wfv RCSB], [https://www.ebi.ac.uk/pdbsum/1wfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wfv ProSAT], [https://www.topsan.org/Proteins/RSGI/1wfv TOPSAN]</span></td></tr>
-
|DOMAIN=
+
</table>
-
|RELATEDENTRY=
+
== Function ==
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wfv OCA], [http://www.ebi.ac.uk/pdbsum/1wfv PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1wfv RCSB]</span>
+
[https://www.uniprot.org/uniprot/MAGI2_HUMAN MAGI2_HUMAN] Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation.<ref>PMID:10760291</ref>
-
}}
+
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wf/1wfv_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wfv ConSurf].
 +
<div style="clear:both"></div>
-
'''Solution structure of the fifth PDZ domain of human membrane associated guanylate kinase inverted-2 (KIAA0705 protein)'''
+
==See Also==
-
 
+
*[[Guanylate kinase 3D structures|Guanylate kinase 3D structures]]
-
 
+
== References ==
-
==About this Structure==
+
<references/>
-
1WFV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WFV OCA].
+
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Inoue, M.]]
+
[[Category: Inoue M]]
-
[[Category: Kigawa, T.]]
+
[[Category: Kigawa T]]
-
[[Category: Koshiba, S.]]
+
[[Category: Koshiba S]]
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
[[Category: Tochio N]]
-
[[Category: Tochio, N.]]
+
[[Category: Yokoyama S]]
-
[[Category: Yokoyama, S.]]
+
-
[[Category: activin receptor interacting protein 1]]
+
-
[[Category: activin type iia receptor]]
+
-
[[Category: actriia]]
+
-
[[Category: acvrip1]]
+
-
[[Category: aip1]]
+
-
[[Category: arip1]]
+
-
[[Category: atrophin-1 interacting protein 1]]
+
-
[[Category: magi-2]]
+
-
[[Category: membrane associated guanylate kinase inverted-2]]
+
-
[[Category: pdz domain]]
+
-
[[Category: riken structural genomics/proteomics initiative]]
+
-
[[Category: rsgi]]
+
-
[[Category: structural genomic]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:35:42 2008''
+

Current revision

Solution structure of the fifth PDZ domain of human membrane associated guanylate kinase inverted-2 (KIAA0705 protein)

PDB ID 1wfv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1wfv"
Personal tools