1d8a
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
==E. COLI ENOYL REDUCTASE/NAD+/TRICLOSAN COMPLEX== | ==E. COLI ENOYL REDUCTASE/NAD+/TRICLOSAN COMPLEX== | ||
| - | <StructureSection load='1d8a' size='340' side='right' caption='[[1d8a]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='1d8a' size='340' side='right'caption='[[1d8a]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1d8a]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1d8a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D8A FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=TCL:TRICLOSAN'>TCL</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d8a OCA], [https://pdbe.org/1d8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d8a RCSB], [https://www.ebi.ac.uk/pdbsum/1d8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d8a ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/FABI_ECOLI FABI_ECOLI] Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis.<ref>PMID:8119879</ref> <ref>PMID:7592873</ref> <ref>PMID:20693992</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d8/1d8a_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d8/1d8a_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
| Line 22: | Line 22: | ||
==See Also== | ==See Also== | ||
| - | *[[Enoyl-Acyl-Carrier Protein Reductase|Enoyl-Acyl-Carrier Protein Reductase]] | + | *[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
| Line 28: | Line 28: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: Baker | + | [[Category: Large Structures]] |
| - | [[Category: Levy | + | [[Category: Baker PJ]] |
| - | [[Category: Rafferty | + | [[Category: Levy CW]] |
| - | [[Category: Rice | + | [[Category: Rafferty JB]] |
| - | [[Category: Roujeinikova | + | [[Category: Rice DW]] |
| - | [[Category: Sedelnikova | + | [[Category: Roujeinikova A]] |
| - | [[Category: Slabas | + | [[Category: Sedelnikova S]] |
| - | [[Category: Stuitje | + | [[Category: Slabas AR]] |
| - | + | [[Category: Stuitje AR]] | |
| - | + | ||
| - | + | ||
Current revision
E. COLI ENOYL REDUCTASE/NAD+/TRICLOSAN COMPLEX
| |||||||||||
