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5v8k

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==Homodimeric reaction center of H. modesticaldum==
==Homodimeric reaction center of H. modesticaldum==
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<StructureSection load='5v8k' size='340' side='right' caption='[[5v8k]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='5v8k' size='340' side='right'caption='[[5v8k]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5v8k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Heliobacterium_modesticaldum Heliobacterium modesticaldum] and [http://en.wikipedia.org/wiki/Heliobacterium_modesticaldum_(strain_atcc_51547_/_ice1) Heliobacterium modesticaldum (strain atcc 51547 / ice1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V8K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V8K FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5v8k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Heliomicrobium_modesticaldum Heliomicrobium modesticaldum] and [https://en.wikipedia.org/wiki/Heliomicrobium_modesticaldum_Ice1 Heliomicrobium modesticaldum Ice1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V8K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5V8K FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AOH:8(1)-OH-Chlorophyll+aF'>AOH</scene>, <scene name='pdbligand=C4D:4,4-Diaponeurosporene'>C4D</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DGG:1-[GLYCEROLYLPHOSPHONYL]-2-[8-(2-HEXYL-CYCLOPROPYL)-OCTANAL-1-YL]-3-[HEXADECANAL-1-YL]-GLYCEROL'>DGG</scene>, <scene name='pdbligand=GB0:Bacteriochlorophyll+g'>GB0</scene>, <scene name='pdbligand=GBF:Bacteriochlorophyll+g'>GBF</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jb0|1jb0]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AOH:8(1)-OH-Chlorophyll+aF'>AOH</scene>, <scene name='pdbligand=C4D:4,4-Diaponeurosporene'>C4D</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DGG:1-[GLYCEROLYLPHOSPHONYL]-2-[8-(2-HEXYL-CYCLOPROPYL)-OCTANAL-1-YL]-3-[HEXADECANAL-1-YL]-GLYCEROL'>DGG</scene>, <scene name='pdbligand=GB0:Bacteriochlorophyll+g'>GB0</scene>, <scene name='pdbligand=GBF:Bacteriochlorophyll+g'>GBF</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v8k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v8k OCA], [http://pdbe.org/5v8k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v8k RCSB], [http://www.ebi.ac.uk/pdbsum/5v8k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v8k ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5v8k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v8k OCA], [https://pdbe.org/5v8k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5v8k RCSB], [https://www.ebi.ac.uk/pdbsum/5v8k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5v8k ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/Q1MX24_9FIRM Q1MX24_9FIRM]
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Reaction centers are pigment-protein complexes that drive photosynthesis by converting light into chemical energy. It is believed that they arose once from a homodimeric protein. The symmetry of a homodimer is broken in heterodimeric reaction center structures, such as those reported previously. The 2.2-A resolution X-ray structure of the homodimeric reaction center/photosystem from the phototroph, Heliobacterium modesticaldum, exhibits perfect C2 symmetry. The core polypeptide dimer and two small subunits coordinate 54 (bacterio)chlorophylls and 2 carotenoids that capture and transfer energy to the electron transfer chain at the center, which performs charge separation and consists of 6 (bacterio)chlorophylls and an iron-sulfur cluster; unlike other reaction centers, it lacks a bound quinone. This structure preserves characteristics of the ancestral reaction center, providing insight into evolution of photosynthesis.
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Structure of a symmetric photosynthetic reaction center-photosystem.,Gisriel C, Sarrou I, Ferlez B, Golbeck JH, Redding KE, Fromme R Science. 2017 Jul 27. pii: eaan5611. doi: 10.1126/science.aan5611. PMID:28751471<ref>PMID:28751471</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 5v8k" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Heliobacterium modesticaldum]]
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[[Category: Heliomicrobium modesticaldum]]
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[[Category: Ferlez, B]]
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[[Category: Heliomicrobium modesticaldum Ice1]]
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[[Category: Fromme, R]]
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[[Category: Large Structures]]
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[[Category: Gisriel, C]]
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[[Category: Ferlez B]]
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[[Category: Golbeck, J]]
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[[Category: Fromme R]]
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[[Category: Redding, K E]]
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[[Category: Gisriel C]]
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[[Category: Sarrou, I]]
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[[Category: Golbeck J]]
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[[Category: Homodimeric]]
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[[Category: Redding KE]]
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[[Category: Photosynthesis]]
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[[Category: Sarrou I]]
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[[Category: Reaction center]]
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Current revision

Homodimeric reaction center of H. modesticaldum

PDB ID 5v8k

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