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5n15

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==First Bromodomain (BD1) from Candida albicans Bdf1 in the unbound form==
==First Bromodomain (BD1) from Candida albicans Bdf1 in the unbound form==
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<StructureSection load='5n15' size='340' side='right' caption='[[5n15]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
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<StructureSection load='5n15' size='340' side='right'caption='[[5n15]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5n15]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N15 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5N15 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5n15]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N15 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5N15 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.37&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5n15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n15 OCA], [http://pdbe.org/5n15 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5n15 RCSB], [http://www.ebi.ac.uk/pdbsum/5n15 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5n15 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5n15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n15 OCA], [https://pdbe.org/5n15 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5n15 RCSB], [https://www.ebi.ac.uk/pdbsum/5n15 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5n15 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BDF1_CANAL BDF1_CANAL]] Transcription factor involved in the expression of a broad class of genes including snRNAs. Required for sporulation and DNA-damage repair. Prevents the spreading of SIR silencing at telomeres and protects histone H4, but not H3, from deacetylation (By similarity).
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[https://www.uniprot.org/uniprot/BDF1_CANAL BDF1_CANAL] Transcription factor involved in the expression of a broad class of genes including snRNAs. Required for sporulation and DNA-damage repair. Prevents the spreading of SIR silencing at telomeres and protects histone H4, but not H3, from deacetylation (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Champleboux, M]]
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[[Category: Candida albicans]]
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[[Category: Chauvel, M]]
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[[Category: Large Structures]]
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[[Category: Cornet, M]]
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[[Category: Champleboux M]]
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[[Category: Courcon, M]]
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[[Category: Chauvel M]]
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[[Category: Enfert, C d]]
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[[Category: Cornet M]]
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[[Category: Ferri, E]]
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[[Category: Courcon M]]
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[[Category: Garnaud, C]]
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[[Category: Ferri E]]
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[[Category: Govin, J]]
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[[Category: Garnaud C]]
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[[Category: Harbut, M]]
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[[Category: Govin J]]
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[[Category: Hull, M]]
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[[Category: Harbut M]]
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[[Category: Kashemirov, B A]]
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[[Category: Hull M]]
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[[Category: Maubon, D]]
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[[Category: Kashemirov BA]]
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[[Category: McKenna, C E]]
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[[Category: Maubon D]]
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[[Category: Mietton, F]]
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[[Category: McKenna CE]]
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[[Category: Petosa, C]]
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[[Category: Mietton F]]
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[[Category: Spittler, D]]
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[[Category: Petosa C]]
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[[Category: Zala, N]]
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[[Category: Spittler D]]
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[[Category: Zhou, Y]]
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[[Category: Zala N]]
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[[Category: Bromodomain]]
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[[Category: Zhou Y]]
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[[Category: Transcription]]
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[[Category: D'Enfert C]]

Current revision

First Bromodomain (BD1) from Candida albicans Bdf1 in the unbound form

PDB ID 5n15

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