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5n7k
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==Crystal structure of the coiled-coil domain of human tricellulin== | ==Crystal structure of the coiled-coil domain of human tricellulin== | ||
| - | <StructureSection load='5n7k' size='340' side='right' caption='[[5n7k]], [[Resolution|resolution]] 2.81Å' scene=''> | + | <StructureSection load='5n7k' size='340' side='right'caption='[[5n7k]], [[Resolution|resolution]] 2.81Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5n7k]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N7K OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5n7k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5N7K FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.81Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5n7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n7k OCA], [https://pdbe.org/5n7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5n7k RCSB], [https://www.ebi.ac.uk/pdbsum/5n7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5n7k ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/MALD2_HUMAN MALD2_HUMAN] Autosomal recessive non-syndromic sensorineural deafness type DFNB. The disease is caused by mutations affecting the gene represented in this entry. |
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/MALD2_HUMAN MALD2_HUMAN] Plays a role in the formation of the epithelial barriers. The separation of the endolymphatic and perilymphatic spaces of the organ of Corti from one another by epithelial barriers is required for normal hearing.<ref>PMID:17186462</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Heinemann U]] |
| - | [[Category: | + | [[Category: Schuetz A]] |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of the coiled-coil domain of human tricellulin
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