4xlp

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==Crystal structure of T.aquaticus transcription initiation complex containing upstream fork promoter==
==Crystal structure of T.aquaticus transcription initiation complex containing upstream fork promoter==
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<StructureSection load='4xlp' size='340' side='right' caption='[[4xlp]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
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<StructureSection load='4xlp' size='340' side='right'caption='[[4xlp]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4xlp]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XLP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XLP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4xlp]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XLP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XLP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xln|4xln]], [[4xlq|4xlq]], [[4xlr|4xlr]], [[4xls|4xls]], [[4xax|4xax]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xlp OCA], [https://pdbe.org/4xlp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xlp RCSB], [https://www.ebi.ac.uk/pdbsum/4xlp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xlp ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xlp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xlp OCA], [http://pdbe.org/4xlp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xlp RCSB], [http://www.ebi.ac.uk/pdbsum/4xlp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xlp ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RPOZ_THEAQ RPOZ_THEAQ]] Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.<ref>PMID:11158566</ref> [[http://www.uniprot.org/uniprot/SIGA_THEAQ SIGA_THEAQ]] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.[HAMAP-Rule:MF_00963]<ref>PMID:11114902</ref> <ref>PMID:11931761</ref>
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[https://www.uniprot.org/uniprot/RPOA_THEAQ RPOA_THEAQ]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4xlp" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4xlp" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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*[[Sigma factor 3D structures|Sigma factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: DNA-directed RNA polymerase]]
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[[Category: Large Structures]]
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[[Category: Synthetic construct]]
[[Category: Thermus aquaticus]]
[[Category: Thermus aquaticus]]
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[[Category: Bae, B]]
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[[Category: Bae B]]
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[[Category: Darst, S A]]
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[[Category: Darst SA]]
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[[Category: Bacterial transcription initiation complex]]
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[[Category: Protein-dna complex]]
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[[Category: Transcription]]
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[[Category: Transcription-dna complex]]
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Current revision

Crystal structure of T.aquaticus transcription initiation complex containing upstream fork promoter

PDB ID 4xlp

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