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5tjn

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==Crystal structure of GTB + B trisaccharide (native)==
==Crystal structure of GTB + B trisaccharide (native)==
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<StructureSection load='5tjn' size='340' side='right' caption='[[5tjn]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
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<StructureSection load='5tjn' size='340' side='right'caption='[[5tjn]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5tjn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TJN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TJN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5tjn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TJN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TJN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGB:alpha-L-Fucp-(1- 2)[alpha-D-Galp-(1- 3)]-beta-D-Galp-O(CH2)7CH3'>BGB</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.47&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5tjk|5tjk]], [[5tjl|5tjl]], [[5tjm|5tjm]], [[5tjo|5tjo]], [[5tjp|5tjp]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=HSH:OCTYL+BETA-D-GALACTOPYRANOSIDE'>HSH</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tjn OCA], [http://pdbe.org/5tjn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tjn RCSB], [http://www.ebi.ac.uk/pdbsum/5tjn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tjn ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tjn OCA], [https://pdbe.org/5tjn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tjn RCSB], [https://www.ebi.ac.uk/pdbsum/5tjn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tjn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN]] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
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[https://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5tjn" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5tjn" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Evans, S V]]
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[[Category: Homo sapiens]]
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[[Category: Gagnon, S M.L]]
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[[Category: Large Structures]]
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[[Category: Legg, M S.G]]
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[[Category: Evans SV]]
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[[Category: Glycosyltransferase]]
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[[Category: Gagnon SML]]
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[[Category: Gt-a fold]]
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[[Category: Legg MSG]]
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[[Category: Histo blood group enzyme]]
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[[Category: Product trisaccharide]]
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[[Category: Transferase]]
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Current revision

Crystal structure of GTB + B trisaccharide (native)

PDB ID 5tjn

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