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5v6r
From Proteopedia
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==Structure of Plexin D1 intracellular domain== | ==Structure of Plexin D1 intracellular domain== | ||
| - | <StructureSection load='5v6r' size='340' side='right' caption='[[5v6r]], [[Resolution|resolution]] 2.70Å' scene=''> | + | <StructureSection load='5v6r' size='340' side='right'caption='[[5v6r]], [[Resolution|resolution]] 2.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5v6r]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V6R OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5v6r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V6R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5V6R FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5v6r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v6r OCA], [https://pdbe.org/5v6r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5v6r RCSB], [https://www.ebi.ac.uk/pdbsum/5v6r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5v6r ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PLXD1_MOUSE PLXD1_MOUSE] Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Mediates anti-angiogenic signaling in response to SEMA3E. Required for normal development of the heart and vasculature.<ref>PMID:15239958</ref> <ref>PMID:17318185</ref> <ref>PMID:18992737</ref> <ref>PMID:19027330</ref> <ref>PMID:19421194</ref> <ref>PMID:22179111</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
| - | *[[Plexin|Plexin]] | + | *[[Plexin 3D structures|Plexin 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: | + | [[Category: Shang G]] |
| - | [[Category: | + | [[Category: Zhang X]] |
Current revision
Structure of Plexin D1 intracellular domain
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