1hu3
From Proteopedia
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==MIDDLE DOMAIN OF HUMAN EIF4GII== | ==MIDDLE DOMAIN OF HUMAN EIF4GII== | ||
| - | <StructureSection load='1hu3' size='340' side='right' caption='[[1hu3]], [[Resolution|resolution]] 2.37Å' scene=''> | + | <StructureSection load='1hu3' size='340' side='right'caption='[[1hu3]], [[Resolution|resolution]] 2.37Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'> | + | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HU3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HU3 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.37Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hu3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hu3 OCA], [https://pdbe.org/1hu3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hu3 RCSB], [https://www.ebi.ac.uk/pdbsum/1hu3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hu3 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/IF4G3_HUMAN IF4G3_HUMAN]] Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Thought to be a functional homolog of EIF4G1.<ref>PMID:9418880</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hu/1hu3_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hu/1hu3_consurf.spt"</scriptWhenChecked> |
| - | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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==See Also== | ==See Also== | ||
| - | *[[Eukaryotic initiation factor|Eukaryotic initiation factor]] | + | *[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Burley | + | [[Category: Large Structures]] |
| - | [[Category: Hellen | + | [[Category: Burley SK]] |
| - | [[Category: Lomakin | + | [[Category: Hellen CUT]] |
| - | [[Category: Marcotrigiano | + | [[Category: Lomakin I]] |
| - | [[Category: Pestova | + | [[Category: Marcotrigiano J]] |
| - | [[Category: Sonenberg | + | [[Category: Pestova TV]] |
| - | + | [[Category: Sonenberg N]] | |
| - | + | ||
| - | + | ||
Current revision
MIDDLE DOMAIN OF HUMAN EIF4GII
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