5o6p
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5o6p is ON HOLD Authors: Bowler, M.W. Description: Structure of beta-phosphoglucomutase D10N mutant in complex with glucose-1,6-bisphosphate [[Cate...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of beta-phosphoglucomutase D10N mutant in complex with glucose-1,6-bisphosphate== | |
| + | <StructureSection load='5o6p' size='340' side='right'caption='[[5o6p]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5o6p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5O6P FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B16:1,6-DI-O-PHOSPHONO-BETA-D-GLUCOPYRANOSE'>B16</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5o6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o6p OCA], [https://pdbe.org/5o6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5o6p RCSB], [https://www.ebi.ac.uk/pdbsum/5o6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5o6p ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PGMB_LACLA PGMB_LACLA] Catalyzes the interconversion of D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), forming beta-D-glucose 1,6-(bis)phosphate (beta-G16P) as an intermediate. The beta-phosphoglucomutase (Beta-PGM) acts on the beta-C(1) anomer of G1P. Glucose or lactose are used in preference to maltose, which is only utilized after glucose or lactose has been exhausted. It plays a key role in the regulation of the flow of carbohydrate intermediates in glycolysis and the formation of the sugar nucleotide UDP-glucose.<ref>PMID:9084169</ref> <ref>PMID:15005616</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Beta-phosphoglucomutase 3D structures|Beta-phosphoglucomutase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Bowler | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Lactococcus lactis]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bowler MW]] | ||
Current revision
Structure of beta-phosphoglucomutase D10N mutant in complex with glucose-1,6-bisphosphate
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