1x87

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[[Image:1x87.gif|left|200px]]
 
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{{Structure
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==2.4A X-ray structure of Urocanase protein complexed with NAD==
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|PDB= 1x87 |SIZE=350|CAPTION= <scene name='initialview01'>1x87</scene>, resolution 2.40&Aring;
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<StructureSection load='1x87' size='340' side='right'caption='[[1x87]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
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<table><tr><td colspan='2'>[[1x87]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X87 FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Urocanate_hydratase Urocanate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.49 4.2.1.49] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK05414 PRK05414]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x87 OCA], [https://pdbe.org/1x87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x87 RCSB], [https://www.ebi.ac.uk/pdbsum/1x87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x87 ProSAT], [https://www.topsan.org/Proteins/MCSG/1x87 TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1x87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x87 OCA], [http://www.ebi.ac.uk/pdbsum/1x87 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1x87 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/HUTU_GEOKA HUTU_GEOKA] Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.[HAMAP-Rule:MF_00577]
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== Evolutionary Conservation ==
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'''2.4A X-ray structure of Urocanase protein complexed with NAD'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x8/1x87_consurf.spt"</scriptWhenChecked>
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1X87 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X87 OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x87 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Urocanate hydratase]]
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[[Category: Collart F]]
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[[Category: Collart, F.]]
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[[Category: Dementieva I]]
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[[Category: Dementieva, I.]]
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[[Category: Gilbreth R]]
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[[Category: Gilbreth, R.]]
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[[Category: Joachimiak A]]
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[[Category: Joachimiak, A.]]
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[[Category: Kossiakoff A]]
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[[Category: Kossiakoff, A.]]
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[[Category: Tereshko V]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Zaborske J]]
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[[Category: Tereshko, V.]]
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[[Category: Zaborske, J.]]
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[[Category: mcsg]]
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[[Category: midwest center for structural genomic]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: putative urocanase protein]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:45:59 2008''
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Current revision

2.4A X-ray structure of Urocanase protein complexed with NAD

PDB ID 1x87

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