5qcj

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'''Unreleased structure'''
 
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The entry 5qcj is ON HOLD
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==Crystal structure of human Cathepsin-S with bound ligand==
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<StructureSection load='5qcj' size='340' side='right'caption='[[5qcj]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5qcj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QCJ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BJY:5-hydroxy-3-{1-[(2S)-2-hydroxy-3-{5-(methylsulfonyl)-3-[4-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-1-yl}propyl]piperidin-4-yl}-1H-pyrrolo[3,2-c]pyridin-5-ium'>BJY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qcj OCA], [https://pdbe.org/5qcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qcj RCSB], [https://www.ebi.ac.uk/pdbsum/5qcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qcj ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
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Authors: Yang, H., Shao, C., Burley, S.
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==See Also==
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*[[Cathepsin 3D structures|Cathepsin 3D structures]]
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Description: Ligand binding to Cathepsin S
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__TOC__
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[[Category: Unreleased Structures]]
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</StructureSection>
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[[Category: Burley, S]]
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[[Category: Homo sapiens]]
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[[Category: Yang, H]]
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[[Category: Large Structures]]
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[[Category: Shao, C]]
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[[Category: Ameriks MK]]
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[[Category: Bembenek SD]]
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[[Category: Burley SK]]
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[[Category: Mirzadegan T]]
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[[Category: Shao C]]
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[[Category: Yang H]]

Current revision

Crystal structure of human Cathepsin-S with bound ligand

PDB ID 5qcj

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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