5v54
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of 5-HT1B receptor in complex with methiothepin== | |
+ | <StructureSection load='5v54' size='340' side='right'caption='[[5v54]], [[Resolution|resolution]] 3.90Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[5v54]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Spodoptera_frugiperda Spodoptera frugiperda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V54 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5V54 FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.9Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=89F:1-methyl-4-[(5~{S})-3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine'>89F</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5v54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v54 OCA], [https://pdbe.org/5v54 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5v54 RCSB], [https://www.ebi.ac.uk/pdbsum/5v54 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5v54 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/5HT1B_HUMAN 5HT1B_HUMAN] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. | ||
- | + | ==See Also== | |
- | + | *[[5-hydroxytryptamine receptor 3D structures|5-hydroxytryptamine receptor 3D structures]] | |
- | + | __TOC__ | |
- | [[Category: | + | </StructureSection> |
- | [[Category: | + | [[Category: Homo sapiens]] |
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Spodoptera frugiperda]] |
- | [[Category: | + | [[Category: Caffrey M]] |
- | [[Category: | + | [[Category: Cai X]] |
- | [[Category: Jiang | + | [[Category: Dai A]] |
- | [[Category: Liu | + | [[Category: Huang CY]] |
- | [[Category: | + | [[Category: Jiang Y]] |
- | [[Category: | + | [[Category: Liu B]] |
- | [[Category: | + | [[Category: Liu P]] |
- | [[Category: | + | [[Category: Melcher K]] |
- | [[Category: | + | [[Category: Wang MT]] |
- | [[Category: | + | [[Category: Wang MW]] |
- | [[Category: Yin | + | [[Category: Xu HE]] |
- | [[Category: | + | [[Category: Xu Y]] |
- | [[Category: | + | [[Category: Yang D]] |
- | [[Category: | + | [[Category: Yin WC]] |
+ | [[Category: Yin Y]] | ||
+ | [[Category: Zhou XE]] | ||
+ | [[Category: De Waal P]] |
Current revision
Crystal structure of 5-HT1B receptor in complex with methiothepin
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