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5xhc
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of T2R-TTL-PO10 complex== | |
| + | <StructureSection load='5xhc' size='340' side='right'caption='[[5xhc]], [[Resolution|resolution]] 2.75Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5xhc]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus], [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Sus_barbatus Sus barbatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XHC FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=87U:(3Z,6Z)-3-[(4-tert-butyl-1H-imidazol-5-yl)methylidene]-6-[[3-(4-fluorophenyl)carbonylphenyl]methylidene]piperazine-2,5-dione'>87U</scene>, <scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xhc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xhc OCA], [https://pdbe.org/5xhc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xhc RCSB], [https://www.ebi.ac.uk/pdbsum/5xhc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xhc ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A0R4I993_SUSBA A0A0R4I993_SUSBA] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.[RuleBase:RU000352][SAAS:SAAS00824325] | ||
| - | + | ==See Also== | |
| - | + | *[[Stathmin-4 3D structures|Stathmin-4 3D structures]] | |
| - | + | *[[Tubulin 3D Structures|Tubulin 3D Structures]] | |
| - | [[Category: | + | *[[Tubulin tyrosine ligase|Tubulin tyrosine ligase]] |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Chu | + | [[Category: Gallus gallus]] |
| - | [[Category: Li | + | [[Category: Large Structures]] |
| + | [[Category: Rattus norvegicus]] | ||
| + | [[Category: Sus barbatus]] | ||
| + | [[Category: Chu Y]] | ||
| + | [[Category: Li W]] | ||
| + | [[Category: Wang Y]] | ||
| + | [[Category: Yang J]] | ||
Current revision
Crystal structure of T2R-TTL-PO10 complex
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Categories: Gallus gallus | Large Structures | Rattus norvegicus | Sus barbatus | Chu Y | Li W | Wang Y | Yang J
