5xnh
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of the branched-chain polyamine synthase (BpsA) in complex with spermidine== | |
+ | <StructureSection load='5xnh' size='340' side='right'caption='[[5xnh]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[5xnh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_kodakarensis_KOD1 Thermococcus kodakarensis KOD1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XNH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XNH FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SPD:SPERMIDINE'>SPD</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xnh OCA], [https://pdbe.org/5xnh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xnh RCSB], [https://www.ebi.ac.uk/pdbsum/5xnh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xnh ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/BPSA_THEKO BPSA_THEKO] Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine. Can also use spermine to produce N(4)-aminopropylspermine.<ref>PMID:24610711</ref> | ||
- | + | ==See Also== | |
- | + | *[[Spermidine synthase 3D structures|Spermidine synthase 3D structures]] | |
- | + | == References == | |
- | [[Category: | + | <references/> |
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Thermococcus kodakarensis KOD1]] | ||
+ | [[Category: Fujita J]] | ||
+ | [[Category: Inoue T]] | ||
+ | [[Category: Mizohata E]] | ||
+ | [[Category: Tse KM]] |
Current revision
Crystal structure of the branched-chain polyamine synthase (BpsA) in complex with spermidine
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