5xv1

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m (Protected "5xv1" [edit=sysop:move=sysop])
Current revision (08:14, 22 November 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5xv1 is ON HOLD until Paper Publication
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==Crystal structure of ATG101-ATG13HORMA==
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<StructureSection load='5xv1' size='340' side='right'caption='[[5xv1]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
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Authors: Kim, B.-W., Song, H.K.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5xv1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XV1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XV1 FirstGlance]. <br>
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Description: Crystal structure of ATG101-ATG13HORMA
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.508&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xv1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xv1 OCA], [https://pdbe.org/5xv1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xv1 RCSB], [https://www.ebi.ac.uk/pdbsum/5xv1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xv1 ProSAT]</span></td></tr>
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[[Category: Kim, B.-W]]
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</table>
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[[Category: Song, H.K]]
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== Function ==
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[https://www.uniprot.org/uniprot/ATG13_HUMAN ATG13_HUMAN] Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.<ref>PMID:19287211</ref> <ref>PMID:19211835</ref> <ref>PMID:19225151</ref> <ref>PMID:21855797</ref> <ref>PMID:18936157</ref> <ref>PMID:21795849</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Kim B-W]]
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[[Category: Song HK]]

Current revision

Crystal structure of ATG101-ATG13HORMA

PDB ID 5xv1

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