5xwe
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of a three finger toxin from Ophiophagus hannah venom== | |
| - | + | <StructureSection load='5xwe' size='340' side='right'caption='[[5xwe]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5xwe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ophiophagus_hannah Ophiophagus hannah]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XWE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xwe OCA], [https://pdbe.org/5xwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xwe RCSB], [https://www.ebi.ac.uk/pdbsum/5xwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xwe ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/3S11H_OPHHA 3S11H_OPHHA] Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.[UniProtKB:P60775] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ophiophagus hannah]] | ||
| + | [[Category: Jobichen C]] | ||
| + | [[Category: Kini RM]] | ||
| + | [[Category: Roy A]] | ||
| + | [[Category: Sivaraman J]] | ||
Current revision
Structure of a three finger toxin from Ophiophagus hannah venom
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