5y8z

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "5y8z" [edit=sysop:move=sysop])
Current revision (10:22, 27 March 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 5y8z is ON HOLD until Paper Publication
+
==Crystal Structure Analysis of the BRD4==
 +
<StructureSection load='5y8z' size='340' side='right'caption='[[5y8z]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[5y8z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y8Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Y8Z FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8Q3:5-bromanyl-N-(3,6-dimethyl-1,2-benzoxazol-5-yl)-2-methoxy-benzenesulfonamide'>8Q3</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5y8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y8z OCA], [https://pdbe.org/5y8z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5y8z RCSB], [https://www.ebi.ac.uk/pdbsum/5y8z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5y8z ProSAT]</span></td></tr>
 +
</table>
 +
== Disease ==
 +
[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
-
Authors: Xu, Y., Zhang, Y., Song, M., Wang, C.
+
==See Also==
-
 
+
*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
-
Description: Crystal Structure Analysis of the BRD4
+
== References ==
-
[[Category: Unreleased Structures]]
+
<references/>
-
[[Category: Xu, Y]]
+
__TOC__
-
[[Category: Zhang, Y]]
+
</StructureSection>
-
[[Category: Song, M]]
+
[[Category: Homo sapiens]]
-
[[Category: Wang, C]]
+
[[Category: Large Structures]]
 +
[[Category: Song M]]
 +
[[Category: Wang C]]
 +
[[Category: Xu Y]]
 +
[[Category: Zhang Y]]

Current revision

Crystal Structure Analysis of the BRD4

PDB ID 5y8z

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5y8z"
Personal tools