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1xsq

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[[Image:1xsq.gif|left|200px]]
 
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{{Structure
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==Crystal structure of ureidoglycolate hydrolase from E.coli. Northeast Structural Genomics Consortium target ET81.==
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|PDB= 1xsq |SIZE=350|CAPTION= <scene name='initialview01'>1xsq</scene>, resolution 1.60&Aring;
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<StructureSection load='1xsq' size='340' side='right'caption='[[1xsq]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
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<table><tr><td colspan='2'>[[1xsq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XSQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XSQ FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Ureidoglycolate_hydrolase Ureidoglycolate hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.19 3.5.3.19] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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|GENE= allA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam04115 Ureidogly_hydro], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG3194 DAL3]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xsq OCA], [https://pdbe.org/1xsq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xsq RCSB], [https://www.ebi.ac.uk/pdbsum/1xsq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xsq ProSAT], [https://www.topsan.org/Proteins/NESGC/1xsq TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xsq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xsq OCA], [http://www.ebi.ac.uk/pdbsum/1xsq PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1xsq RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/ALLA_ECOLI ALLA_ECOLI] Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the anaerobic utilization of allantoin as sole nitrogen source. Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate.<ref>PMID:10601204</ref> <ref>PMID:24107613</ref>
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== Evolutionary Conservation ==
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'''Crystal structure of ureidoglycolate hydrolase from E.coli. Northeast Structural Genomics Consortium target ET81.'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xs/1xsq_consurf.spt"</scriptWhenChecked>
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1XSQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XSQ OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xsq ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Ureidoglycolate hydrolase]]
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[[Category: Abashidze M]]
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[[Category: Abashidze, M.]]
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[[Category: Acton TB]]
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[[Category: Acton, T B.]]
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[[Category: Hunt JF]]
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[[Category: Hunt, J F.]]
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[[Category: Kuzin AP]]
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[[Category: Kuzin, A P.]]
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[[Category: Ma L-C]]
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[[Category: Ma, L C.]]
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[[Category: Montelione GT]]
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[[Category: Montelione, G T.]]
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[[Category: Tong L]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Vorobiev SM]]
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[[Category: Tong, L.]]
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[[Category: Xiao R]]
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[[Category: Vorobiev, S M.]]
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[[Category: Xiao, R.]]
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[[Category: et81]]
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[[Category: nesg]]
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[[Category: northeast structural genomics consortium]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomic]]
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[[Category: x-ray]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:54:08 2008''
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Current revision

Crystal structure of ureidoglycolate hydrolase from E.coli. Northeast Structural Genomics Consortium target ET81.

PDB ID 1xsq

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