5ybh

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(New page: '''Unreleased structure''' The entry 5ybh is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures)
Current revision (10:22, 27 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5ybh is ON HOLD until Paper Publication
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==Structural of the highly conserved ATPase from type III secretion system of bacterial pathogens==
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<StructureSection load='5ybh' size='340' side='right'caption='[[5ybh]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5ybh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YBH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YBH FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ybh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ybh OCA], [https://pdbe.org/5ybh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ybh RCSB], [https://www.ebi.ac.uk/pdbsum/5ybh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ybh ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SCTN_SHIFL SCTN_SHIFL] ATPase component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:26947936, PubMed:27770024, PubMed:29595954). Acts as a molecular motor to provide the energy that is required for the export of proteins (Probable). Required for type III secretion apparatus (T3SA) formation, proper protein secretion, host cell invasion and virulence (PubMed:26947936, PubMed:27770024, PubMed:31162724). May play a critical role in T3SS substrate recognition, disassembly of the effector/chaperone complex and unfolding of the effector in an ATP-dependent manner prior to secretion (By similarity).[UniProtKB:P0A1B9]<ref>PMID:26947936</ref> <ref>PMID:27770024</ref> <ref>PMID:29595954</ref> <ref>PMID:31162724</ref> <ref>PMID:26947936</ref> <ref>PMID:27770024</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Shigella flexneri]]
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[[Category: Cui S]]
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[[Category: Gao X]]
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[[Category: Mu Z]]

Current revision

Structural of the highly conserved ATPase from type III secretion system of bacterial pathogens

PDB ID 5ybh

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