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1y1o

From Proteopedia

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[[Image:1y1o.gif|left|200px]]
 
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{{Structure
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==X-ray crystal Structure of Penicillin-binding protein-related factor A from Bacillus stearothermophilus==
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|PDB= 1y1o |SIZE=350|CAPTION= <scene name='initialview01'>1y1o</scene>, resolution 2.20&Aring;
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<StructureSection load='1y1o' size='340' side='right'caption='[[1y1o]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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<table><tr><td colspan='2'>[[1y1o]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y1O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Y1O FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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|GENE= RBSTP1992 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1422 Geobacillus stearothermophilus])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK02234 recU]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1y1o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y1o OCA], [https://pdbe.org/1y1o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1y1o RCSB], [https://www.ebi.ac.uk/pdbsum/1y1o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1y1o ProSAT], [https://www.topsan.org/Proteins/MCSG/1y1o TOPSAN]</span></td></tr>
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|RELATEDENTRY=[[1rzn|1rzn]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1y1o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y1o OCA], [http://www.ebi.ac.uk/pdbsum/1y1o PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1y1o RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/RECU_GEOKA RECU_GEOKA] Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.[HAMAP-Rule:MF_00130]<ref>PMID:12237459</ref>
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== Evolutionary Conservation ==
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'''X-ray crystal Structure of Penicillin-binding protein-related factor A from Bacillus stearothermophilus'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/y1/1y1o_consurf.spt"</scriptWhenChecked>
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1Y1O is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y1O OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1y1o ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Collart, F.]]
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[[Category: Collart F]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak A]]
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[[Category: Li, H.]]
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[[Category: Li H]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Moy S]]
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[[Category: Moy, S.]]
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[[Category: Osipiuk J]]
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[[Category: Osipiuk, J.]]
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[[Category: mcsg]]
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[[Category: midwest center for structural genomic]]
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[[Category: penicillin-binding protein]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:57:38 2008''
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Current revision

X-ray crystal Structure of Penicillin-binding protein-related factor A from Bacillus stearothermophilus

PDB ID 1y1o

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