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5wjr

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(New page: ==2-Se-T2/4-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant== <StructureSection load='5wjr' size='340' side='right' caption='5wjr, [[Resolution|resolut...)
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==2-Se-T2/4-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant==
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==High resolution native hexamer DNA and RNA hybrid in complex with RNase H catalytic domain D132N mutant==
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<StructureSection load='5wjr' size='340' side='right' caption='[[5wjr]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='5wjr' size='340' side='right'caption='[[5wjr]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5wjr]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WJR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WJR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5wjr]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Alkalihalobacillus_halodurans_C-125 Alkalihalobacillus halodurans C-125] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WJR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wjr OCA], [http://pdbe.org/5wjr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wjr RCSB], [http://www.ebi.ac.uk/pdbsum/5wjr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wjr ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wjr OCA], [https://pdbe.org/5wjr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wjr RCSB], [https://www.ebi.ac.uk/pdbsum/5wjr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wjr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RNH1_BACHD RNH1_BACHD]] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
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[https://www.uniprot.org/uniprot/RNH1_HALH5 RNH1_HALH5] Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<ref>PMID:15989951</ref>
==See Also==
==See Also==
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*[[Ribonuclease|Ribonuclease]]
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ribonuclease H]]
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[[Category: Alkalihalobacillus halodurans C-125]]
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[[Category: Fang, Z]]
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[[Category: Large Structures]]
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[[Category: Huang, Z]]
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[[Category: Synthetic construct]]
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[[Category: Hydrolase]]
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[[Category: Fang Z]]
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[[Category: Hydrolase-dna-rna complex]]
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[[Category: Huang Z]]

Current revision

High resolution native hexamer DNA and RNA hybrid in complex with RNase H catalytic domain D132N mutant

PDB ID 5wjr

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