6b6g
From Proteopedia
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(New page: '''Unreleased structure''' The entry 6b6g is ON HOLD Authors: Description: Category: Unreleased Structures) |
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- | '''Unreleased structure''' | ||
- | + | ==Crystal Structure of GABA Aminotransferase bound to (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid, an Potent Inactivatorfor the Treatment of Addiction== | |
+ | <StructureSection load='6b6g' size='340' side='right'caption='[[6b6g]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[6b6g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6B6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6B6G FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=RMT:(3R,4E)-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]cyclopent-1-ene-1,3-dicarboxylic+acid'>RMT</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6b6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6b6g OCA], [https://pdbe.org/6b6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6b6g RCSB], [https://www.ebi.ac.uk/pdbsum/6b6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6b6g ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/GABT_PIG GABT_PIG] Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine. | ||
- | + | ==See Also== | |
- | + | *[[Aminotransferase 3D structures|Aminotransferase 3D structures]] | |
- | + | __TOC__ | |
- | [[Category: | + | </StructureSection> |
+ | [[Category: Large Structures]] | ||
+ | [[Category: Sus scrofa]] | ||
+ | [[Category: Juncosa JI]] | ||
+ | [[Category: Le LV]] | ||
+ | [[Category: Liu D]] | ||
+ | [[Category: Mascarenhas R]] | ||
+ | [[Category: Moschitto MJ]] | ||
+ | [[Category: Silverman RB]] | ||
+ | [[Category: Takaya K]] |
Current revision
Crystal Structure of GABA Aminotransferase bound to (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid, an Potent Inactivatorfor the Treatment of Addiction
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Categories: Large Structures | Sus scrofa | Juncosa JI | Le LV | Liu D | Mascarenhas R | Moschitto MJ | Silverman RB | Takaya K