5mih
From Proteopedia
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==Crystal structure of the lectin LecA from Pseudomonas aeruginosa in complex with a phenyl-epoxy-galactopyranoside== | ==Crystal structure of the lectin LecA from Pseudomonas aeruginosa in complex with a phenyl-epoxy-galactopyranoside== | ||
| - | <StructureSection load='5mih' size='340' side='right' caption='[[5mih]], [[Resolution|resolution]] 1.80Å' scene=''> | + | <StructureSection load='5mih' size='340' side='right'caption='[[5mih]], [[Resolution|resolution]] 1.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5mih]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MIH OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5mih]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MIH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MIH FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7NU: | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7NU:phenyl+6,7-anhydro-D-glycero-beta-D-galacto-heptopyranoside'>7NU</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ETE:2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>ETE</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mih OCA], [https://pdbe.org/5mih PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mih RCSB], [https://www.ebi.ac.uk/pdbsum/5mih PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mih ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PA1L_PSEAE PA1L_PSEAE] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5mih" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5mih" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Galactose-binding lectin|Galactose-binding lectin]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Hauk | + | [[Category: Large Structures]] |
| - | [[Category: Hofmann | + | [[Category: Pseudomonas aeruginosa PAO1]] |
| - | [[Category: Imberty | + | [[Category: Hauk D]] |
| - | [[Category: Joachim | + | [[Category: Hofmann M]] |
| - | [[Category: Muller | + | [[Category: Imberty A]] |
| - | [[Category: Sommer | + | [[Category: Joachim I]] |
| - | [[Category: Titz | + | [[Category: Muller R]] |
| - | [[Category: Varrot | + | [[Category: Sommer R]] |
| - | [[Category: Wagner | + | [[Category: Titz A]] |
| - | + | [[Category: Varrot A]] | |
| - | + | [[Category: Wagner S]] | |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of the lectin LecA from Pseudomonas aeruginosa in complex with a phenyl-epoxy-galactopyranoside
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Categories: Large Structures | Pseudomonas aeruginosa PAO1 | Hauk D | Hofmann M | Imberty A | Joachim I | Muller R | Sommer R | Titz A | Varrot A | Wagner S
