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2dg2

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==Crystal Structure of Mouse Apolipoprotein A-I Binding Protein==
==Crystal Structure of Mouse Apolipoprotein A-I Binding Protein==
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<StructureSection load='2dg2' size='340' side='right' caption='[[2dg2]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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<StructureSection load='2dg2' size='340' side='right'caption='[[2dg2]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dg2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DG2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DG2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dg2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DG2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Apoa1bp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dg2 OCA], [https://pdbe.org/2dg2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dg2 RCSB], [https://www.ebi.ac.uk/pdbsum/2dg2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dg2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dg2 OCA], [http://pdbe.org/2dg2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dg2 RCSB], [http://www.ebi.ac.uk/pdbsum/2dg2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dg2 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NNRE_MOUSE NNRE_MOUSE] Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.[HAMAP-Rule:MF_03159]<ref>PMID:21994945</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dg/2dg2_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dg/2dg2_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Chruszcz, M]]
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[[Category: Mus musculus]]
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[[Category: Cymborowski, M]]
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[[Category: Chruszcz M]]
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[[Category: Herr, J C]]
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[[Category: Cymborowski M]]
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[[Category: Jha, K N]]
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[[Category: Herr JC]]
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[[Category: Minor, W]]
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[[Category: Jha KN]]
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[[Category: Shumilin, I A]]
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[[Category: Minor W]]
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[[Category: Zheng, H]]
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[[Category: Shumilin IA]]
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[[Category: Disordered n-terminus]]
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[[Category: Zheng H]]
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[[Category: Protein binding]]
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Current revision

Crystal Structure of Mouse Apolipoprotein A-I Binding Protein

PDB ID 2dg2

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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