This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1k8x

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:54, 16 August 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Crystal Structure Of AlphaT183V Mutant Of Tryptophan Synthase From Salmonella Typhimurium==
==Crystal Structure Of AlphaT183V Mutant Of Tryptophan Synthase From Salmonella Typhimurium==
-
<StructureSection load='1k8x' size='340' side='right' caption='[[1k8x]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
+
<StructureSection load='1k8x' size='340' side='right'caption='[[1k8x]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1k8x]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K8X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K8X FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1k8x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium] and [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K8X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K8X FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptophan_synthase Tryptophan synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.20 4.2.1.20] </span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k8x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k8x OCA], [http://pdbe.org/1k8x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1k8x RCSB], [http://www.ebi.ac.uk/pdbsum/1k8x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1k8x ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k8x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k8x OCA], [https://pdbe.org/1k8x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k8x RCSB], [https://www.ebi.ac.uk/pdbsum/1k8x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k8x ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/TRPA_SALTY TRPA_SALTY]] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. [[http://www.uniprot.org/uniprot/TRPB_SALTY TRPB_SALTY]] The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
+
[https://www.uniprot.org/uniprot/TRPA_SALTY TRPA_SALTY] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k8/1k8x_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k8/1k8x_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
Line 29: Line 29:
</div>
</div>
<div class="pdbe-citations 1k8x" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1k8x" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Salty]]
+
[[Category: Large Structures]]
-
[[Category: Tryptophan synthase]]
+
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
-
[[Category: Arac, D]]
+
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
-
[[Category: Dunn, M F]]
+
[[Category: Arac D]]
-
[[Category: Kulik, V]]
+
[[Category: Dunn MF]]
-
[[Category: Niks, D]]
+
[[Category: Kulik V]]
-
[[Category: Schlichting, I]]
+
[[Category: Niks D]]
-
[[Category: Siedel, R]]
+
[[Category: Schlichting I]]
-
[[Category: Weyand, M]]
+
[[Category: Siedel R]]
-
[[Category: Helix]]
+
[[Category: Weyand M]]
-
[[Category: Lyase]]
+

Current revision

Crystal Structure Of AlphaT183V Mutant Of Tryptophan Synthase From Salmonella Typhimurium

PDB ID 1k8x

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1k8x"
Personal tools