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1khp

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==Monoclinic form of papain/ZLFG-DAM covalent complex==
==Monoclinic form of papain/ZLFG-DAM covalent complex==
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<StructureSection load='1khp' size='340' side='right' caption='[[1khp]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='1khp' size='340' side='right'caption='[[1khp]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1khp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Carpa Carpa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KHP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KHP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1khp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Carica_papaya Carica papaya]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KHP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KHP FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=0HQ:DIAZOMETHANE'>0HQ</scene>, <scene name='pdbligand=PHQ:BENZYL+CHLOROCARBONATE'>PHQ</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1pad|1pad]], [[5pad|5pad]], [[6pad|6pad]], [[9pap|9pap]], [[1ppn|1ppn]], [[2pad|2pad]], [[1pe6|1pe6]], [[1pip|1pip]], [[1ppp|1ppp]], [[1ppd|1ppd]], [[1pop|1pop]], [[1stf|1stf]], [[1cvz|1cvz]], [[1khq|1khq]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0HQ:DIAZOMETHANE'>0HQ</scene>, <scene name='pdbligand=PHQ:BENZYL+CHLOROCARBONATE'>PHQ</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Papain Papain], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.2 3.4.22.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1khp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1khp OCA], [https://pdbe.org/1khp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1khp RCSB], [https://www.ebi.ac.uk/pdbsum/1khp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1khp ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1khp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1khp OCA], [http://pdbe.org/1khp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1khp RCSB], [http://www.ebi.ac.uk/pdbsum/1khp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1khp ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PAPA1_CARPA PAPA1_CARPA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kh/1khp_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kh/1khp_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 1khp" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1khp" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Papain|Papain]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Carpa]]
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[[Category: Carica papaya]]
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[[Category: Papain]]
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[[Category: Large Structures]]
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[[Category: Grzonka, Z]]
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[[Category: Grzonka Z]]
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[[Category: Jankowska, E]]
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[[Category: Jankowska E]]
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[[Category: Janowski, R]]
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[[Category: Janowski R]]
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[[Category: Jaskolski, M]]
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[[Category: Jaskolski M]]
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[[Category: Kozak, M]]
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[[Category: Kozak M]]
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[[Category: Diazomethylketone inhibitor]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Irreversible inhibitor]]
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[[Category: Protease inhibitor]]
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Current revision

Monoclinic form of papain/ZLFG-DAM covalent complex

PDB ID 1khp

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