1l3z

<StructureSection load='1l3z' size='340' side='right' caption='[[1l3z]], [[Resolution|resolution]] 2.01&Aring;' scene=''>

<table><tr><td colspan='2'>[[1l3z]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L3Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L3Z FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l3z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l3z OCA], [http://pdbe.org/1l3z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1l3z RCSB], [http://www.ebi.ac.uk/pdbsum/1l3z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1l3z ProSAT]</span></td></tr>

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== Publication Abstract from PubMed ==

The crystal structure of an alternating RNA heptamer r(GUAUACA) has been determined to 2.0 A resolution and refined to an R(work) of 17.1% and R(free) of 18.5% using 2797 reflections. The heptamer crystallized in the space group C222 with a unit cell of a = 25.74, b = 106.58, c = 30.26 A and two independent strands in the asymmetric unit. Each heptamer forms a duplex with its symmetry-related strand and each duplex contains six Watson-Crick base pairs and 3'-end adenosine overhangs. Therefore, two kinds of duplex (duplex 1 and duplex 2) are formed. Duplexes 1 stack on each other forming a pseudo-continuous column, which is typical of the RNA packing mode, while duplex 2 is typical of A-DNA packing with its termini in abutting interactions. Overhang adenine residues stack within the duplexes with C3'-endo sugar pucker and C2'-endo sugar pucker in duplexes 1 and 2, respectively. A Na+ ion in the crystal lattice is water bridged to two N1 atoms of symmetry-related A7 bases.

The crystal structure of an alternating RNA heptamer r(GUAUACA) forming a six base-paired duplex with 3'-end adenine overhangs.,Shi K, Pan B, Sundaralingam M Nucleic Acids Res. 2003 Mar 1;31(5):1392-7. PMID:12595546<ref>PMID:12595546</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>

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<div class="pdbe-citations 1l3z" style="background-color:#fffaf0;"></div>

== References ==

<references/>

[[Category: Pan, B]]

[[Category: Shi, K]]

[[Category: Sundaralingam, M]]

[[Category: Rna]]