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1wmq

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==Structure of the HutP antitermination complex bound to a single stranded region of hut mRNA==
==Structure of the HutP antitermination complex bound to a single stranded region of hut mRNA==
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<StructureSection load='1wmq' size='340' side='right' caption='[[1wmq]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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<StructureSection load='1wmq' size='340' side='right'caption='[[1wmq]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1wmq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WMQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WMQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1wmq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WMQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WMQ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HIS:HISTIDINE'>HIS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1wmq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wmq OCA], [http://pdbe.org/1wmq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1wmq RCSB], [http://www.ebi.ac.uk/pdbsum/1wmq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1wmq ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HIS:HISTIDINE'>HIS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wmq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wmq OCA], [https://pdbe.org/1wmq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wmq RCSB], [https://www.ebi.ac.uk/pdbsum/1wmq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wmq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HUTP_BACSU HUTP_BACSU]] Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.[HAMAP-Rule:MF_00779]
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[https://www.uniprot.org/uniprot/HUTP_BACSU HUTP_BACSU] Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.[HAMAP-Rule:MF_00779]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wm/1wmq_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wm/1wmq_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus globigii migula 1900]]
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[[Category: Bacillus subtilis]]
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[[Category: Kumar, P K.R]]
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[[Category: Large Structures]]
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[[Category: Kumarevel, T S]]
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[[Category: Kumar PKR]]
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[[Category: Mizuno, H]]
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[[Category: Kumarevel TS]]
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[[Category: Antitermination]]
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[[Category: Mizuno H]]
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[[Category: Hutp]]
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[[Category: Protein-rna complex]]
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[[Category: Rna binding]]
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[[Category: Transcription regulation]]
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[[Category: Transcription-rna complex]]
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Current revision

Structure of the HutP antitermination complex bound to a single stranded region of hut mRNA

PDB ID 1wmq

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