1spv

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==Crystal Structure of the Putative Phosphatase of Escherichia coli, Northeast Structural Genomoics Target ER58==
==Crystal Structure of the Putative Phosphatase of Escherichia coli, Northeast Structural Genomoics Target ER58==
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<StructureSection load='1spv' size='340' side='right' caption='[[1spv]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='1spv' size='340' side='right'caption='[[1spv]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1spv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SPV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SPV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1spv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SPV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SPV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1spv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1spv OCA], [http://pdbe.org/1spv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1spv RCSB], [http://www.ebi.ac.uk/pdbsum/1spv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1spv ProSAT], [http://www.topsan.org/Proteins/NESGC/1spv TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1spv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1spv OCA], [https://pdbe.org/1spv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1spv RCSB], [https://www.ebi.ac.uk/pdbsum/1spv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1spv ProSAT], [https://www.topsan.org/Proteins/NESGC/1spv TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/YMDB_ECOLI YMDB_ECOLI]] Deacetylates O-acetyl-ADP ribose. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation.<ref>PMID:19141481</ref> <ref>PMID:21257746</ref>
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[https://www.uniprot.org/uniprot/YMDB_ECOLI YMDB_ECOLI] Deacetylates O-acetyl-ADP ribose. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation.<ref>PMID:19141481</ref> <ref>PMID:21257746</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sp/1spv_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sp/1spv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Acton, T B]]
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[[Category: Large Structures]]
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[[Category: Forouhar, F]]
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[[Category: Acton TB]]
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[[Category: Hunt, J F]]
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[[Category: Forouhar F]]
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[[Category: Lee, I]]
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[[Category: Hunt JF]]
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[[Category: Montelione, G T]]
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[[Category: Lee I]]
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[[Category: Structural genomic]]
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[[Category: Montelione GT]]
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[[Category: Tong, L]]
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[[Category: Tong L]]
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[[Category: Vorobiev, S M]]
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[[Category: Vorobiev SM]]
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[[Category: Xiao, R]]
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[[Category: Xiao R]]
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[[Category: Alpha/beta monomeric protein]]
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[[Category: Nesg]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Structural genomoic]]
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[[Category: Unknown function]]
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Current revision

Crystal Structure of the Putative Phosphatase of Escherichia coli, Northeast Structural Genomoics Target ER58

PDB ID 1spv

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