2gil

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==Structure of the extremely slow GTPase Rab6A in the GTP bound form at 1.8 resolution==
==Structure of the extremely slow GTPase Rab6A in the GTP bound form at 1.8 resolution==
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<StructureSection load='2gil' size='340' side='right' caption='[[2gil]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
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<StructureSection load='2gil' size='340' side='right'caption='[[2gil]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2gil]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GIL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GIL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2gil]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GIL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GIL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gil OCA], [http://pdbe.org/2gil PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gil RCSB], [http://www.ebi.ac.uk/pdbsum/2gil PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2gil ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gil OCA], [https://pdbe.org/2gil PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gil RCSB], [https://www.ebi.ac.uk/pdbsum/2gil PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gil ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RAB6A_HUMAN RAB6A_HUMAN]] Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity.
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[https://www.uniprot.org/uniprot/RAB6A_HUMAN RAB6A_HUMAN] Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gi/2gil_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gi/2gil_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 2gil" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2gil" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Alexandrov, K]]
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[[Category: Large Structures]]
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[[Category: Bergbrede, T]]
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[[Category: Alexandrov K]]
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[[Category: Pylypenko, O]]
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[[Category: Bergbrede T]]
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[[Category: Rak, A]]
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[[Category: Pylypenko O]]
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[[Category: Gtpase-fold]]
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[[Category: Rak A]]
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[[Category: Protein transport]]
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[[Category: Protein-nucleotide complex]]
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Current revision

Structure of the extremely slow GTPase Rab6A in the GTP bound form at 1.8 resolution

PDB ID 2gil

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